A single-step new route has been developed to synthesize 2-pentanone from biomass-derived furfural via simultaneous hydrodeoxygenation (HDO), ring-opening (RO) and hydrogenation reactions over a bi-metallic Cu–Ni/SBA-15 catalyst in a fixed-bed continuous flow reactor. Cu–Ni/SBA-15 catalysts were synthesized by the incipient wetness impregnation method. Synthesized catalysts were characterized by X-ray diffraction (XRD), temperature-programmed reduction (H₂-TPR), TEM mapping, SEM, ICP-AES. Ammonia temperature-programmed desorption (NH₃-TPD) analysis of catalysts revealed that moderate acidity of 10Cu–5Ni/SBA-15 catalyst favoured a high yield of 2-pentanone. DFT calculation, indicate the adsorption energy and the reaction mechanism of the molecules on the surface of 10Cu–5Ni/SBA-15 play a vital role for the desired product. The catalyst system was found highly active and selective, yielding (78%) of 2-pentanone under mild reaction conditions. The effect of reaction temperature was studied in detail, and time on stream analysis confirmed the catalyst is long-lasting stable up to 20 h of reaction duration.

已开发出一种单步新路线，在双金属 Cu-Ni/SBA-15 催化剂上通过同时加氢脱氧 (HDO)、开环 (RO) 和加氢反应从生物质衍生的糠醛合成 2-戊酮。固定床连续流反应器。Cu-Ni/SBA-15催化剂采用初湿浸渍法合成。通过X射线衍射（XRD）、程序升温还原（H ₂ -TPR）、TEM图谱、SEM、ICP-AES对合成的催化剂进行表征。氨程序升温脱附 (NH ₃-TPD) 对催化剂的分析表明 10Cu-5Ni/SBA-15 催化剂的中等酸性有利于 2-戊酮的高产率。DFT 计算表明，10Cu-5Ni/SBA-15 表面分子的吸附能和反应机理对所需产品起着至关重要的作用。发现该催化剂体系具有高活性和选择性，在温和的反应条件下产率 (78%) 2-戊酮。详细研究了反应温度的影响，流时间分析证实该催化剂在长达 20 小时的反应持续时间内是持久稳定的。