Previous genome-wide studies have identified an association between the rs2106261 single-nucleotide polymorphism (SNP) in the zinc finger homeobox 3 (ZFHX3) gene and an increased risk of atrial fibrillation (AF). However, this association remains controversial, since conflicting results have been reported in previous studies. We aimed to investigate the association between the ZFHX3 rs2106261 polymorphism and susceptibility to AF.

中文翻译：

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锌指同源框 3 基因中 rs2106261 多态性与房颤风险之间的关联：来自符合 PRISMA 的荟萃分析的证据。

先前的全基因组研究已经确定了锌指同源框 3 (ZFHX3) 基因中的 rs2106261 单核苷酸多态性 (SNP) 与心房颤动 (AF) 风险增加之间的关联。然而，这种关联仍然存在争议，因为之前的研究报告了相互矛盾的结果。我们旨在研究 ZFHX3 rs2106261 多态性和 AF 易感性之间的关联。