Abstract

In this study, eight polyphenol derivatives were prepared to serve as green antifoulants. Polyphenol derivatives, which can hinder the growth of bacteria and algae and decrease the adhesion of some marine organisms, showed good AF activity; in particular, the activities of these derivatives were much higher than those of the corresponding polyphenols. The antibacterial rates of the products (20 μg ml⁻¹) exceeded 88%. Moreover, the anti-algal rates of compounds a3, b1, b2, b3 and b4 (15 μg ml⁻¹) were over 57% at 240 h, but these compounds showed low toxicity, and the 120 h EC₅₀ values were > 6.60 μg ml⁻¹. In addition, there were fewer marine microorganisms on the test panel than on the control. The above results show that some polyphenol derivatives possess relatively high antibacterial, anti-algal, and AF activity; more notably, the addition of chlorine atoms and amide groups can further increase the activity of these derivatives.

摘要

在这项研究中，制备了八种多酚衍生物作为绿色防污剂。多酚衍生物能抑制细菌和藻类的生长，减少一些海洋生物的粘附，表现出良好的AF活性；特别是，这些衍生物的活性远高于相应的多酚。^{产品（20 μg ml -1} ）的抗菌率超过88%。^{此外，化合物a3、b1、b2、b3和b4（15 μg ml -1}）在240 h时的抗藻率超过57%，但这些化合物毒性较低，120 h EC ₅₀值> 6.60微克毫升^-1. 此外，测试板上的海洋微生物数量少于对照组。上述结果表明，一些多酚衍生物具有较高的抗菌、抗藻和AF活性；更值得注意的是，氯原子和酰胺基团的加入可以进一步提高这些衍生物的活性。