Introduction acute urinary tract obstruction (aUTO) is a common finding in older hospitalised patients. Anecdotal reports described hyponatraemia in patients with aUTO, which subsides rapidly with relief of the obstruction. The aim of this study was to determine the incidence, severity and subsequent correction of hyponatraemia in patients with aUTO. Methods this is a prospective, single-centre, observational study including inpatients in the internal medicine and geriatric wards. A total of 204 patients were investigated, 104 with aUTO and 100 controls. The prevalence, severity and associations of hyponatraemia between aUTO and control patients were compared. Results the incidence of hyponatraemia was similar in aUTO and control groups 28% versus 22%, respectively (P = 0.42). However, the incidence of severe hyponatraemia was significantly higher in the study group 7% versus 1% (P = 0.04). Mean sodium level was lower in hyponatremic patients with aUTO 127.7 ± 5.9 mEq/l versus 130.8 ± 3 mEq/l (P = 0.013). Serum sodium remained largely unchanged in the control group (∆Na 1.5 ± 2.3 mEq/l) but increased significantly within 48 hours following catheter insertion in patients with urinary retention (∆Na 5.3 ± 4.2 mEq/l overall in the aUTO group and 9.6 ± 3 mEq/l in those with urinary retention and severe hyponatraemia (P = 0.002)).

中文翻译：

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前瞻性确定老年急性尿路梗阻住院患者低钠血症的发生率和严重程度

简介 急性尿路梗阻 (aUTO) 是老年住院患者的常见发现。轶事报道描述了 aUTO 患者的低钠血症，随着梗阻的缓解，低钠血症迅速消退。本研究的目的是确定 aUTO 患者低钠血症的发生率、严重程度和随后的纠正。方法 这是一项前瞻性、单中心、观察性研究，包括内科和老年病房的住院患者。共调查了 204 名患者，其中 104 名使用自动驾驶仪，100 名对照。比较了 aUTO 和对照组患者低钠血症的发生率、严重程度和相关性。结果 aUTO 组和对照组的低钠血症发生率相似，分别为 28% 和 22%（P = 0.42）。然而，研究组的严重低钠血症发生率显着高于 7% 和 1%（P = 0.04）。aUTO 为 127.7 ± 5.9 mEq/l 和 130.8 ± 3 mEq/l 的低钠血症患者的平均钠水平较低（P = 0.013）。对照组的血清钠基本保持不变（ΔNa 1.5 ± 2.3 mEq/l），但在尿潴留患者插入导管后 48 小时内显着增加（ΔNa 5.3 ± 4.2 mEq/l 总体在 aUTO 组和 9.6 ±尿潴留和严重低钠血症患者为 3 mEq/l (P = 0.002)。