Ventricular remodeling is related to the renin-angiotensin-aldosterone system, immune system, and various cytokines involved in inflammation, apoptosis, and cell signal regulation. Accumulated studies have shown that traditional Chinese medicine can significantly inhibit the process of ventricular remodeling, which may be related to the mechanism mentioned above. Here, we conducted a system overview to critically review the cellular and molecular mechanism of traditional Chinese medicine on ventricular remodeling. We mainly searched PubMed for basic research about the anti-ventricular remodeling of traditional Chinese medicine in 5 recent years, and then objectively summarized these researches. We included more than 25 kinds of Chinese herbal medicines including Qi-Li-Qian-Xin, Qi-Shen-Yi-Qi Pill, Xin-Ji-Er-Kang Formula, and Yi-Qi-Wen-Yang Decoction, and found that they can inhibit ventricular remodeling effectively through multi-components and multi-action targets, which are promoting the clinical application of traditional Chinese medicine.

心室重构与肾素-血管紧张素-醛固酮系统、免疫系统以及参与炎症、细胞凋亡和细胞信号调节的各种细胞因子有关。积累的研究表明，中药可以显着抑制心室重构的过程，这可能与上述机制有关。在这里，我们进行了系统概述，以批判性地回顾中药对心室重构的细胞和分子机制。我们主要在PubMed中检索了近5年来有关中药抗心室重构的基础研究，然后客观地总结了这些研究。我们收录了超过25种中草药，包括气理千心、气肾益气丸、心机二康方、