OBJECTIVE We aimed to study open-angle glaucoma in association with somatic comorbidities in the total population of adults in Region Stockholm. METHODS The study population included all living persons aged 19 years and above who resided in Stockholm County, Sweden, on 1 January 2017 (N = 1 703 675). Subjects with specified diseases were identified with data from all registered consultations and hospital stays during 2008-2019. As outcome, the risk of being associated with a diagnosis of open-angle glaucoma was identified during 2012-2018. Analyses were performed by gender, controlling for age and socio-economic status. Age-adjusted odds ratios (ORs) with 95% confidence intervals (95% CI) for women and men with open-angle glaucoma, using individuals without this as referents, were calculated. Socio-economic status was assessed based on the neighbourhood the subjects lived in. RESULTS In total, 16,299 cases of open-angle glaucoma were identified during 2012-2018, 9204 women and 7095 men. Higher fully adjusted OR (95% CI) for risk of being associated with open-angle glaucoma was for women and men with diabetes 1.138 (1.074-1.207) and 1.216 (1.148-1.289), cancer 1.175 (1.120-1.233) and 1.106 (1.048-1.166), hypertension 1.372 (1.306-1.440) and 1.243 (1.179-1.311); and for women with thyroid diseases 1.086 (1.030-1.146), chronic lung diseases 1.153 (1.093-1.216), and inflammatory arthropathies 1.132 (1.006-1.275). Higher glaucoma incidence was observed in individuals residing in high socio-economic status neighbourhoods. CONCLUSION The risk of glaucoma is increased in some somatic diseases, especially in individuals with diabetes, hypertension and cancer; and in higher socio-economic neighbourhoods as compared to lower socio-economic neighbourhoods.

中文翻译：

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斯德哥尔摩人群的全身性疾病及其与开角型青光眼的关系。

目的 我们旨在研究斯德哥尔摩地区成人总人口中开角型青光眼与躯体合并症的关系。方法 研究人群包括 2017 年 1 月 1 日居住在瑞典斯德哥尔摩县的所有 19 岁及以上在世的人（N = 1 703 675）。使用 2008-2019 年期间所有登记咨询和住院的数据确定患有特定疾病的受试者。结果，在 2012-2018 年期间确定了与开角型青光眼诊断相关的风险。分析按性别进行，控制年龄和社会经济地位。计算了患有开角型青光眼的女性和男性的年龄调整优势比 (OR) 和 95% 置信区间 (95% CI)，使用没有此指标的个体作为参照。根据受试者居住的社区评估社会经济状况。结果在 2012-2018 年期间，总共确定了 16,299 例开角型青光眼，其中 9204 名女性和 7095 名男性。与开角型青光眼相关的风险较高的完全校正 OR (95% CI) 是女性和男性糖尿病 1.138 (1.074-1.207) 和 1.216 (1.148-1.289)，癌症 1.175 (1.120-1.233) 和 1.106 ( 1.048-1.166)，高血压 1.372 (1.306-1.440) 和 1.243 (1.179-1.311)；对于患有甲状腺疾病 1.086 (1.030-1.146)、慢性肺病 1.153 (1.093-1.216) 和炎症性关节病 1.132 (1.006-1.275) 的女性。在居住在高社会经济地位社区的个体中观察到较高的青光眼发病率。结论 青光眼的风险在一些躯体疾病中增加，尤其是在糖尿病患者中，高血压和癌症；与较低的社会经济社区相比，较高的社会经济社区。