Emerging evidence suggests socioeconomic disadvantage may increase risk for eating disorders (EDs). However, there are very few studies on the association between disadvantage and EDs, and all have focused on individual-level risk factors (e.g., family income). Neighborhood disadvantage (i.e., elevated poverty and reduced resources in one's neighborhood) is associated with increased risk for anxiety/depression and poor physical health. To date, no studies have examined phenotypic associations between neighborhood disadvantage and disordered eating, or how any form of disadvantage may interact with genetic individual differences in risk for EDs. We examined phenotypic and etiologic associations between neighborhood disadvantage and disordered eating in 2,922 girls ages 8-17 from same-sex twin pairs recruited through the Michigan State University Twin Registry. Parents rated the twins on nine items assessing core disordered eating symptoms (e.g., weight preoccupation, binge eating), and neighborhood disadvantage was calculated from 17 indicators of contextual disadvantage (e.g., median home value, neighborhood unemployment). Puberty was measured using the Pubertal Development Scale to examine whether associations were consistent across development. At a phenotypic level, greater neighborhood disadvantage was associated with significantly greater disordered eating symptoms in girls at all stages of puberty (β = .07). Moreover, Genotype × Environment models showed that girls living in more disadvantaged neighborhoods exhibited stronger and earlier (i.e., during pre/early puberty) activation of genetic influences on disordered eating. Results highlight the critical importance of considering contextual disadvantage in research on etiology and risk for disordered eating, and the need for increased screening and treatment for EDs in disadvantaged youth. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

中文翻译：

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背景很重要：邻里不利与女孩饮食失调的增加和遗传影响的早期激活有关。

新出现的证据表明，社会经济劣势可能会增加饮食失调 (ED) 的风险。然而，关于不利条件与 ED 之间关系的研究很少，并且都集中在个人层面的风险因素（例如，家庭收入）上。邻里劣势（即邻里贫困加剧和资源减少）与焦虑/抑郁和身体健康状况不佳的风险增加有关。迄今为止，还没有研究检查过邻里不利条件与饮食失调之间的表型关联，或者任何形式的不利条件如何与 ED 风险的遗传个体差异相互作用。我们检查了 2 中邻里不利条件与饮食失调之间的表型和病因学关联，通过密歇根州立大学双胞胎登记处招募的 922 名 8-17 岁的同性双胞胎女孩。父母对这对双胞胎进行九项评估核心饮食失调症状（例如，体重偏重、暴饮暴食）的评分，并根据环境劣势的 17 个指标（例如，房屋价值中位数、邻里失业率）计算邻里劣势。使用青春期发育量表测量青春期，以检查相关性在整个发育过程中是否一致。在表型水平上，更大的邻里劣势与青春期所有阶段女孩的饮食失调症状显着增加有关（β = .07）。此外，基因型 × 环境模型表明，生活在更贫困社区的女孩表现得更强壮、更早（即，在青春期前/青春期早期）激活遗传对饮食失调的影响。结果强调了在研究饮食失调的病因和风险时考虑背景不利因素的重要性，以及增加对处于不利地位的青年 ED 的筛查和治疗的必要性。（PsycInfo 数据库记录 (c) 2021 APA，保留所有权利）。