In "One-Stage, Limited-Resection Epilepsy Surgery for Bottom-of-Sulcus Dysplasia," Macdonald-Laurs et al. described the performance of corticectomy guided by MRI and electrocorticography (ECoG) in 38 patients with bottom-of-sulcus dysplasia (BOSD). They found that at a median of 6 years postop, 87% of patients were seizure free and noted that their outcomes are similar to those reported in a small series of patients with BOSD who underwent stereotactic thermocoagulation (STC) and laser interstitial thermal therapy (LITT). Hu et al. reported that based on their recent LITT trial, in which they found that 6 of 7 (86%) patients with BOSD were seizure-free 6 months postop, they recommend minimally invasive procedures for BOSD. Harvey et al. agreed with the use of STC or LITT for BOSD in locations that are not easily accessible via a small craniotomy. However, these procedures preclude the use of ECoG to determine epileptogenicity, histopathologic confirmation, and genetic testing of the tissues. In addition, STC and LITT pose risk to surrounding normal cortex and are not widely available. The authors all agree that there is a need for additional long-term outcome data using different treatment strategies in larger cohorts of patients with BOSD.

Macdonald-Laurs 等人在“针对脑沟底部发育不良的一期有限切除癫痫手术”中。描述了在 38 名脑沟发育不良 (BOSD) 患者中，在 MRI 和皮层电图 (ECoG) 指导下进行的皮质切除术的表现。他们发现，在术后 6 年中位数，87% 的患者没有癫痫发作，并指出他们的结果与接受立体定向热凝 (STC) 和激光间质热疗 (LITT) 的 BOSD 患者的小系列报道的结果相似。 ）。胡等人。报告说，根据他们最近的 LITT 试验，他们发现 7 名 BOSD 患者中有 6 名 (86%) 术后 6 个月无癫痫发作，他们建议对 BOSD 进行微创手术。哈维等人。同意在不易通过小开颅手术进入的位置对 BOSD 使用 STC 或 LITT。然而，这些程序排除了使用 ECoG 来确定致癫痫性、组织病理学确认和组织基因检测的可能性。此外，STC 和 LITT 会对周围的正常皮层构成风险，因此并未广泛使用。作者都同意，需要在更大的 BOSD 患者队列中使用不同的治疗策略获得额外的长期结果数据。