Agrobacterium radiobacter is a Gram-negative bacillus and a rare cause of endophthalmitis. An 85-year-male presented with late-onset endophthalmitis associated with exposure of an inferonasal Baerveldt tube. The patient was initially treated with anterior chamber paracentesis and intravitreal antibiotics. Aqueous humor culture revealed A. radiobacter resistant to cefazolin, ceftazidime, amikacin, tobramycin, and trimethoprim-sulfamethoxazole. Subsequently, the patient underwent explantation of the glaucoma drainage implant (GDI). After initial improvement, the patient had clinical worsening and was diagnosed with recurrence. Subsequent treatment involved explantation of the second GDI in addition to pars plana vitrectomy with silicone oil infusion, intraocular lens removal, and administration of intravitreal antibiotics. Visual acuity improved but remained at count fingers at 2 weeks. This is the first reported patient with A. radiobacter endophthalmitis associated with an exposed GDI. This report illustrates the resistant nature of this organism in addition to the efficacy of silicone oil administration and intraocular prosthesis explantation.
Case Rep Ophthalmol 2021;12:921–926

中文翻译：

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与 Baerveldt 管暴露相关的放射性农杆菌眼内炎

放射性农杆菌是一种革兰氏阴性杆菌，是一种罕见的眼内炎病因。一名 85 岁男性因暴露于鼻下 Baerveldt 管而出现迟发性眼内炎。该患者最初接受前房穿刺术和玻璃体内抗生素治疗。房水培养显示A. radiobacter对头孢唑啉、头孢他啶、阿米卡星、妥布霉素和甲氧苄啶-磺胺甲恶唑耐药。随后，该患者接受了青光眼引流植入物（GDI）的外植。初步改善后，患者出现临床恶化并被诊断为复发。随后的治疗包括第二个 GDI 的外植，以及玻璃体切除术和硅油注入、人工晶状体摘除和玻璃体内抗生素的使用。视力有所改善，但在 2 周时仍保持在数指上。这是首例报道的与暴露的 GDI 相关的A. 放射性眼内炎患者。该报告说明了该生物体的抗性特性以及硅油给药和人工眼内假体移植的功效。
Case Rep Ophthalmol 2021；12:921–926