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Supramolecular biomaterials for bio-imaging and imaging-guided therapy.
European Journal of Nuclear Medicine and Molecular Imaging ( IF 9.1 ) Pub Date : 2021-11-24 , DOI: 10.1007/s00259-021-05622-7
Beibei Xie 1 , Yuan-Fu Ding 1 , Mingju Shui 1 , Ludan Yue 1 , Cheng Gao 1, 2 , Ian W Wyman 3 , Ruibing Wang 1, 2
Affiliation  

Benefiting from their unique advantages, including reversibly switchable structures, good biocompatibility, facile functionalization, and sensitive response to biological stimuli, supramolecular biomaterials have been widely applied in biomedicine. In this review, the representative achievements and trends in the design of supramolecular biomaterials (mainly those derived from biomacromolecules) with specific macromolecules including peptides, deoxyribonucleic acid, and polysaccharides, as well as their applications in bio-imaging and imaging-guided therapy are summarized. This review will serve as an important summary and "go for" reference for explorations of the applications of supramolecular biomaterials in bio-imaging and image-guided therapy, and will promote the development of supramolecular chemistry as an emerging interdisciplinary research area.

中文翻译:

用于生物成像和成像引导治疗的超分子生物材料。

超分子生物材料凭借其独特的优势,包括可逆结构、良好的生物相容性、易于功能化和对生物刺激的敏感反应,在生物医学中得到了广泛的应用。本文综述了多肽、脱氧核糖核酸、多糖等特定大分子超分子生物材料(主要是生物大分子衍生材料)设计的代表性成果和趋势,以及它们在生物成像和成像引导治疗中的应用。 . 本综述将为探索超分子生物材料在生物成像和影像引导治疗中的应用提供重要的总结和“参考”,
更新日期:2021-11-24
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