Due to the feasibility of running continuous enzymatic reaction and product separation in a single operation, enzymatic membrane reactors (EMRs) are increasingly applied in the areas of biotechnology, (bio)chemistry, agro-food, and energy. By the use of different membrane cut-offs, enhanced separation selectivity can be obtained during the production of fine chemicals which vary in molecular sizes. Within this review, available designs of EMR are discussed based on membrane functions, hydrodynamic and filtration characteristics. Further, various applications of EMRs are outlined and tabulated, especially in the agro-food, pharmaceutical, environmental, and energy sectors. As a well-known problem in membrane technology, fouling and its circumventions especially in size-exclusion EMR are also critically discussed. Several own and literature results are presented to give overall concepts of EMR operation and used to describe future research trends within the scope of this reactor design.

由于在单个操作中进行连续酶促反应和产品分离的可行性，酶促膜反应器 (EMR) 越来越多地应用于生物技术、（生物）化学、农业食品和能源领域。通过使用不同的膜截断值，可以在分子大小不同的精细化学品的生产过程中获得更高的分离选择性。在这篇综述中，基于膜功能、流体动力学和过滤特性讨论了 EMR 的可用设计。此外，还概述并列出了 EMR 的各种应用，特别是在农业食品、制药、环境和能源部门。作为膜技术中的一个众所周知的问题，污染及其规避尤其是在尺寸排阻 EMR 中也受到了批判性的讨论。