Ocular Immunology and Inflammation ( IF 3.3 ) Pub Date : 2021-11-19 , DOI: 10.1080/09273948.2021.1988988 Eliza Anthony 1 , Prabu Baskaran 2 , Archana Rajamani 2 , Anand Rajendran 2
ABSTRACT
Purpose
To report a case of bilateral occlusive vasculitis associated with retinitis pigmentosa (RP).
Method
Case report.
Case report
A 34-year male presented with blurred vision in left eye (OS) for two weeks and right eye (OD) for one day. He had night blindness for five years. His best corrected visual acuity (BCVA) was OD 20/63 and OS 20/200. Ophthalmoscopy revealed bilateral RP with OD inflammatory central retinal vein occlusion (CRVO) and OS occlusive vasculitis with bilateral macular edema. Presumed intraocular tuberculosis (IOTB) was suspected based on clinical features, positive Mantoux and high-resolution computed tomography chest findings. Oral steroids and antitubercular therapy (ATT) were started. OD received six intravitreal ranibizumab injections. At his 7-month follow-up, BCVA improved, OD 20/40 and OS 20/80.
Conclusion
RP rarely can be associated with presumed IOTB. Oral steroids with ATT are helpful; however, in inflammatory CRVO, intravitreal ranibizumab can give good results.
中文翻译:
双侧闭塞性血管炎伴有色素性视网膜炎 - 病例报告
摘要
目的
报告一例与色素性视网膜炎(RP)相关的双侧闭塞性血管炎病例。
方法
案例报告。
案例报告
一名 34 岁男性因左眼 (OS) 视力模糊两周和右眼 (OD) 视力模糊一天而就诊。他有五年的夜盲症。他的最佳矫正视力 (BCVA) 是 OD 20/63 和 OS 20/200。检眼镜检查显示双侧 RP 伴有 OD 炎症性视网膜中央静脉阻塞 (CRVO) 和 OS 闭塞性血管炎伴双侧黄斑水肿。根据临床特征、Mantoux 阳性和高分辨率计算机断层扫描胸部检查结果,怀疑可能患有眼内结核 (IOTB)。开始口服类固醇和抗结核治疗 (ATT)。OD 接受了六次玻璃体内雷珠单抗注射。在他 7 个月的随访中,BCVA 有所改善,OD 20/40 和 OS 20/80。
结论
RP 很少与假定的 IOTB 相关联。含 ATT 的口服类固醇有帮助;然而,在炎症性 CRVO 中,玻璃体内注射雷珠单抗可以产生良好的效果。