ABSTRACT

Background

In accordance with worldwide data, the Robert Koch Institute (RKI) has reported a constant increase of syphilis cases in Germany over the past decade.

Methods

We analysed the data of all patients, referred to a Department of Ophthalmology in a tertiary referral centre in Düsseldorf, Germany between 2008 and 2019, who were tested for syphilis. The epidemiologic, demographic, clinical, diagnostic and therapeutic data were retrieved from the records and evaluated in a retrospective, descriptive, non-comparative study.

Results

Syphilis serology was positive in 32/1840 (1.7%) patients, and was evenly distributed over this period. 26 (81.3%) were male, 19 (59.4%) belonged to a risk group. Ocular syphilis was the primary diagnosis for 29 patients (90.6%). The most frequent manifestation was uveitis (n = 20, 62.5%). By the end of therapy, 19 patients (59.4%) had an improved visual acuity.

Conclusion

The incidence of ocular syphilis cases has remained stable over the last decade.

中文翻译：

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眼梅毒：在德国眼科参考中心超过 11 年的经验

摘要

背景

根据全球数据，罗伯特科赫研究所 (RKI) 报告称，过去十年德国的梅毒病例不断增加。

方法

我们分析了 2008 年至 2019 年间转诊到德国杜塞尔多夫一家三级转诊中心眼科的所有患者的数据，这些患者接受了梅毒检测。从记录中检索流行病学、人口统计学、临床、诊断和治疗数据，并在回顾性、描述性、非比较研究中进行评估。

结果

32/1840 (1.7%) 名患者的梅毒血清学呈阳性，并且在此期间分布均匀。男性26人（81.3%），高危人群19人（59.4%）。眼部梅毒是 29 名患者 (90.6%) 的主要诊断。最常见的表现是葡萄膜炎 (n = 20, 62.5%)。到治疗结束时，19 名患者 (59.4%) 的视力有所改善。

结论

在过去十年中，眼部梅毒病例的发病率一直保持稳定。