Purpose

To evaluate the effect of 1 full year of the coronavirus disease 2019 (COVID-19) pandemic on clinical presentation of acute, primary rhegmatogenous retinal detachment (RRD).

Design

Single-center, retrospective observational cohort study.

Methods

Patients were divided into 2 cohorts: consecutive patients treated for primary RRD during the COVID-19 pandemic (March 9, 2020, to March 7, 2021; pandemic cohort) and patients treated during the corresponding time in previous year (March 11, 2019, to March 8, 2020; control cohort). Main outcome measures: Proportion of patients presenting with macula-involving (mac-off) or macula-sparring (mac-on) RRD.

Results

A total of 952 patients in the pandemic cohort and 872 patients in the control cohort were included. Demographic factors were similar. Compared with the control cohort, a significantly greater number of pandemic cohort patients presented with mac-off RRDs ([60.92%] pandemic, [48.17%] control, P = .0001) and primary proliferative vitreoretinopathy ([15.53%] pandemic, [6.9%] control, P = .0001). Pandemic cohort patients (10.81%) had significantly higher rates of lost to follow-up compared with the control cohort (4.43%; P = .0001). Patients new to our clinic demonstrated a significant increase in mac-off RRDs in the pandemic cohort (65.35%) compared with the control cohort (50.40%; P = .0001). Pandemic cohort patients showed worse median final best-corrected visual acuity (0.30 logarithm of the minimum angle of resolution) compared with the control cohort (0.18 logarithm of the minimum angle of resolution; P = .0001).

Conclusions

Patients with primary RRD during the first year of the COVID-19 pandemic were more likely to have mac-off disease, present with primary proliferative vitreoretinopathy, be lost to follow-up, and have worse final best-corrected visual acuity outcomes.

中文翻译：

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COVID-19 大流行第一年原发性孔源性视网膜脱离临床表现的趋势

目的

评估 2019 年冠状病毒病 (COVID-19) 大流行一年对急性原发性孔源性视网膜脱离 (RRD) 临床表现的影响。

设计

单中心、回顾性观察性队列研究。

方法

患者分为 2 个队列：在 COVID-19 大流行期间（2020 年 3 月 9 日至 2021 年 3 月 7 日；大流行队列）期间接受原发性 RRD 治疗的连续患者和在前一年相应时间（2019 年 3 月 11 日，至 2020 年 3 月 8 日；对照组）。主要结果测量：出现黄斑累及 (mac-off) 或黄斑辅助 (mac-on) RRD 的患者比例。

结果

共纳入大流行队列中的 952 名患者和对照组中的 872 名患者。人口因素相似。与对照组相比，出现 mac-off RRD（[60.92%] 大流行，[48.17%] 对照，P  = .0001）和原发性增殖性玻璃体视网膜病变（[15.53%] 大流行，[ 6.9%] 对照，P  = .0001)。与对照组（4.43%； P  = .0001）相比，大流行队列患者（10.81%）的失访率显着更高。与对照组 (50.40%; P = .0001)。与对照组（最小分辨角的 0.18 对数； P  = .0001）相比，大流行队列患者的最终最佳矫正视力中位数（最小分辨角的对数 0.30 ）更差。

结论

在 COVID-19 大流行的第一年患有原发性 RRD 的患者更有可能患有 mac-off 病，出现原发性增殖性玻璃体视网膜病变，失访，最终最佳矫正视力结果更差。