Myocardial flow reserve represents the ratio of myocardial blood flow between stress and rest, giving functional information about both macrocirculation and microcirculation; it has been reported extensively in positron emission tomography, with an increase in diagnostic performance, providing important prognostic information and being a powerful tool to guide therapy. Advances in single photon emission computed tomography, with the widespread availability of “cadmium zinc telluride” single photon emission computed tomography cameras, raise the question of myocardial flow reserve use in daily clinical practice. In this article, we review the pathophysiology of myocardial blood flow and myocardial flow reserve, and the initial data available from single photon emission computed tomography myocardial blood flow and myocardial flow reserve evaluation; we also discuss potential limitations to the wider implementation of flow evaluation in single photon emission computed tomography.

心肌血流储备代表应激与静息状态下心肌血流量的比值，给出大循环和微循环的功能信息；它已在正电子发射断层扫描中得到广泛报道，可提高诊断性能，提供重要的预后信息，并成为指导治疗的有力工具。随着“碲化镉锌”单光子发射计算机断层扫描相机的广泛应用，单光子发射计算机断层扫描的进展提出了日常临床实践中心肌血流储备使用的问题。在本文中，我们回顾了心肌血流和心肌血流储备的病理生理学，以及单光子发射计算机断层扫描心肌血流和心肌血流储备评估的初步数据；