Aim: This study aimed to report a case of vitreous and optic nerve infiltration of a primary adrenal B lymphoma. Case Report: An 81-year-old patient consulted for decrease in vision in the left eye and pain with ocular movements during the last week. The patient was being treated with chemotherapy for an adrenal gland diffuse large B-cell lymphoma. On examination, vitritis was seen in both eyes and optic disc edema in his left eye. After an extensive study based on orbital and brain magnetic resonance imaging and vitreous cytology, an ocular infiltration by systemic B lymphoma was confirmed. A treatment based on intravitreal methotrexate was carried out, achieving the regression of the vitreous infiltration and resolution of the optic disc edema. Systemic B lymphoma metastasizing ocular structures is extremely infrequent. The manifestations may mimic an inflammatory disease. Ophthalmologists should be aware of these manifestations and consider among the masquerade syndromes.
Case Rep Ophthalmol 2021;12:915–920

中文翻译：

---

肾上腺 B 淋巴瘤的玻璃体和视神经浸润

目的：本研究旨在报告一例原发性肾上腺 B 淋巴瘤的玻璃体和视神经浸润病例。案例报告：一名 81 岁的患者在上周因左眼视力下降和眼球运动疼痛而就诊。该患者正在接受化疗治疗肾上腺弥漫性大 B 细胞淋巴瘤。查体，双眼可见玻璃体炎，左眼视盘水肿。在基于眼眶和脑磁共振成像以及玻璃体细胞学的广泛研究后，证实了全身性 B 淋巴瘤的眼部浸润。进行了基于玻璃体内甲氨蝶呤的治疗，实现了玻璃体浸润的消退和视盘水肿的消退。转移眼部结构的系统性 B 淋巴瘤极为罕见。这些表现可能类似于炎症性疾病。
Case Rep Ophthalmol 2021；12:915–920