Purpose: 

To describe the outcomes of the inverted internal limiting membrane flap technique without postoperative face-down positioning for macular hole (MH) closure.

Methods: 

This retrospective longitudinal study identified patients who had undergone surgical repair for large (>400 µm), idiopathic MHs and did not maintain face-down positioning postoperatively. Outcome measures included anatomical success, defined as confirmation of hole closure by the optical coherence tomography scan and functional success and defined as improved best-corrected visual acuity from baseline at the last follow-up.

Results: 

Of the 63 eyes enrolled in the study, 94% patients (59 of 63) achieved anatomical success and 91% patients (57 of 63) achieved functional success. Fifteen (15) of these patients presented with a MH >600 µm. This subgroup achieved an anatomical success rate of 93% and a functional success rate of 87%. Statistically significant improvement in best-corrected visual acuity was demonstrated for all subgroups of MH size (P < 0.001).

Conclusion: 

We report a high success rate of large, idiopathic MH closure with the inverted internal limiting membrane flap technique without postoperative face-down positioning. The results described in this study are favorable. However, larger studies with prospective design are warranted to explore this further.

中文翻译：

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倒置内限位膜瓣技术，无需术后面朝下定位黄斑裂孔修复

目的： 

描述没有术后面朝下定位的倒置内界膜瓣技术用于黄斑裂孔 (MH) 闭合的结果。

方法： 

这项回顾性纵向研究确定了因大 (>400 µm ) 特发性 MH接受手术修复且术后未保持面朝下定位的患者。结果测量包括解剖成功，定义为通过光学相干断层扫描确认孔闭合和功能成功，并定义为在最后一次随访中从基线改善最佳矫正视力。

结果： 

在参加研究的 63 只眼中，94% 的患者（63 只中的 59 只）实现了解剖成功，91% 的患者（63 只中的 57 只）实现了功能成功。这些患者中有十五 (15) 名 MH > 600 µm。该亚组的解剖成功率为 93%，功能成功率为 87%。MH 大小的所有亚组的最佳矫正视力都有统计学意义的改善（P < 0.001）。

结论： 

我们报告了使用倒置内界膜瓣技术实现大型特发性 MH 闭合的高成功率，而无需术后面朝下定位。本研究中描述的结果是有利的。然而，有必要进行更大规模的前瞻性设计研究来进一步探索这一点。