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The diagnostic incremental value of 131I SPECT-CT scan compared to planar 131I WBS for differentiated thyroid carcinoma: A single institutional experience
Journal of Radiation Research and Applied Sciences ( IF 1.7 ) Pub Date : 2021-11-11 , DOI: 10.1080/16878507.2021.1994241
Essam M. Alkhybari 1 , Salman M. Albeshan 2 , Bander M. Alanazi 3 , Dalal M. Alqahtani 4 , Hala K. Abokhater 5 , Sundus H. Albakhiti 6 , Intidhar E. Ghanem 5
Affiliation  

ABSTRACT

This study investigated the usefulness of iodine-131 (131I) single-photon emission computed-tomography/computed-tomography (SPECT-CT) in conjunction with whole-body scan (WBS) planar imaging for the management of a patient presenting with differentiated thyroid carcinoma (DTC). A total of 100 patients with DTC post-total thyroidectomy were included in the study. The foci of 131I uptake were classified as neck site and outside the neck site by WBS planar and SPECT-CT imaging. SPECT-CT incrementally identified 141 neck sites and 217 distant neck foci compared to 139 at the neck site and 197 at the outside neck site identified by planar imaging. For the neck site, SPECT-CT downstaged 27 foci of 32 for indeterminate thyroid remnants at the neck site. Regarding sites distant to the neck, the SPECT-CT analysis led to the correct downstaging of two false-positive foci of suspicious uptake within the lung and bone, which were noted as metastases on planar images. SPECT-CT correctly upstaged one focus of iodine activity observed in the left arm as contamination on planar images, subsequently corrected as a metastatic bone lesion. The use of 131I SPECT-CT scans increased the incremental diagnostic data compared with 131I WBS planar scan imaging alone, which could change patient management. 



中文翻译:

与平面 131I WBS 相比,131I SPECT-CT 扫描对分化型甲状腺癌的诊断增量价值:单一机构经验

摘要

本研究调查了碘 131 ( 131 I) 单光子发射计算机断层扫描/计算机断层扫描 (SPECT-CT) 与全身扫描 (WBS) 平面成像相结合的有效性,用于管理出现分化的患者。甲状腺癌(DTC)。该研究共纳入了 100 名甲状腺全切除术后 DTC 患者。131的焦点 通过 WBS 平面和 SPECT-CT 成像,I 摄取分为颈部位点和颈部位点外。SPECT-CT 逐渐识别出 141 个颈部位点和 217 个远处颈部病灶,而平面成像识别出的颈部位点为 139 个,颈部外侧位点为 197 个。对于颈部部位,SPECT-CT 对颈部部位的不确定甲状腺残余物的 32 个病灶中的 27 个病灶进行了降期。对于远离颈部的部位,SPECT-CT 分析导致肺和骨内可疑摄取的两个假阳性病灶的正确降级,这些病灶在平面图像上被标记为转移。SPECT-CT 正确地将左臂中观察到的一个碘活动焦点作为平面图像上的污染进行了升级,随后被纠正为转移性骨病变。使用 131与单独的131 I WBS 平面扫描成像相比,I SPECT-CT 扫描增加了增量诊断数据 ,这可能会改变患者管理。 

更新日期:2021-12-16
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