Evidence and risk indicators of non-random sampling in clinical trials in implant dentistry: A systematic appraisal,Journal of Clinical Periodontology

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Evidence and risk indicators of non-random sampling in clinical trials in implant dentistry: A systematic appraisal
Journal of Clinical Periodontology ( IF 6.7 ) Pub Date : 2021-11-07 , DOI: 10.1111/jcpe.13571
Jun-Yu Shi _{1,

2,

3,

4,

5} , Xiao Zhang _{1,

2,

3,

4,

5} , Shu-Jiao Qian _{1,

2,

3,

4,

5} , Shi-Min Wei _{1,

2,

3,

4,

5} , Kai-Xiao Yan _{1,

2,

3,

4,

5} , Min Xu _{1,

2,

3,

4,

5} , Hong-Chang Lai _{1,

2,

3,

4,

5} , Maurizio S Tonetti _{1,

2,

3,

4,

5,

6}

Affiliation

Analysis of distribution of p-values of continuous differences between test and controls after randomization provides evidence of unintentional error, non-random sampling, or data fabrication in randomized controlled trials (RCTs). We assessed evidence of highly unusual distributions of baseline characteristics of subjects enrolled in clinical trials in implant dentistry.

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