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IRFinder-S: a comprehensive suite to discover and explore intron retention
Genome Biology ( IF 12.3 ) Pub Date : 2021-11-08 , DOI: 10.1186/s13059-021-02515-8
Claudio Lorenzi 1 , Sylvain Barriere 1 , Katharina Arnold 1 , Reini F Luco 1 , Andrew J Oldfield 1 , William Ritchie 1
Affiliation  

Accurate quantification and detection of intron retention levels require specialized software. Building on our previous software, we create a suite of tools called IRFinder-S, to analyze and explore intron retention events in multiple samples. Specifically, IRFinder-S allows a better identification of true intron retention events using a convolutional neural network, allows the sharing of intron retention results between labs, integrates a dynamic database to explore and contrast available samples, and provides a tested method to detect differential levels of intron retention.

中文翻译:

IRFinder-S:发现和探索内含子保留的综合套件

内含子保留水平的准确定量和检测需要专门的软件。在我们之前的软件的基础上,我们创建了一套名为 IRFinder-S 的工具,用于分析和探索多个样本中的内含子保留事件。具体来说,IRFinder-S 允许使用卷积神经网络更好地识别真正的内含子保留事件,允许在实验室之间共享内含子保留结果,集成动态数据库以探索和对比可用样本,并提供检测差异水平的测试方法内含子保留。
更新日期:2021-11-08
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