International Ophthalmology ( IF 1.6 ) Pub Date : 2021-11-02 , DOI: 10.1007/s10792-021-02114-3 Sevim Ayca Seyyar 1 , Alper Mete 2 , Sabit Kimyon 2 , Nesime Setge Tıskaoğlu 3
Purpose
To evaluate the outcomes of corneal collagen cross-linking performed with customized epithelial debridement technique in progressive keratoconic corneas.
Materials and methods
Forty eyes of 40 patients were included in the study. We performed an ophthalmologic examination and recorded the uncorrected visual acuity, best corrected visual acuity (BCVA), central corneal thickness at the thinnest point (t-CCT), flat meridian keratometry (K1), steep meridian keratometry (K2), endothelial cell density (ECC), hexagonal cells (HEX), and coefficient of variation of cell areas (CV) measured preoperatively and at the 1st, 3rd, 6th and 12th months postoperatively.
Results
The mean UCVA and BCVA were increased (p < 0.05). The mean flattest and steepest K readings were decreased (p < 0.05). The mean t-CCT decreased in the first months after treatment and increased after 6 months. The mean t-CCT was thicker at 12 months compared to pretreatment status (p < 0.05). The mean ECC and CV were not significantly different between follow-up intervals (p > 0.05). The mean HEX was statistically increased (p > 0.05).
Conclusions
Corneal collagen cross-linking performed with customized epithelial debridement technique is a successful alternative method for stopping the progression of keratoconus after 12 months of treatment.
中文翻译:
角膜胶原交联定制地形引导上皮清创的结果
目的
评估使用定制上皮清创技术在进行性圆锥角膜中进行角膜胶原交联的结果。
材料和方法
该研究包括 40 名患者的 40 只眼睛。我们进行了眼科检查并记录了裸眼视力、最佳矫正视力(BCVA)、最薄点中央角膜厚度(t-CCT)、平子午角膜曲率(K1)、陡子子眼角膜曲率(K2)、内皮细胞密度(ECC)、六角形细胞 (HEX) 和细胞面积变异系数 (CV) 在术前和术后第 1、3、6 和 12 个月测量。
结果
平均 UCVA 和 BCVA 增加(p < 0.05)。平均最平坦和最陡 K 读数降低 ( p < 0.05)。平均 t-CCT 在治疗后的头几个月下降,在治疗 6 个月后上升。与治疗前状态相比,12 个月时的平均 t-CCT 更厚(p < 0.05)。平均ECC和CV在随访间隔之间没有显着差异(p >0.05)。平均 HEX 显着增加 ( p > 0.05)。
结论
使用定制的上皮清创技术进行的角膜胶原交联是一种成功的替代方法,可在治疗 12 个月后阻止圆锥角膜的进展。