PURPOSE Evaluating the effect of a single peripheral triangular mark to ensure the correct anterior-posterior graft orientation in DMEK. METHODS Retrospective study of patients scheduled for DMEK due to Fuchs endothelial dystrophy and divided into 2 study groups: Group -M (n = 184) had no mark of the EDM (Endothelial Descemet membrane) and group + M (n = 193) had a triangular peripheral mark. Follow-up time was 1 year after surgery. RESULTS The postoperative graft turning and Re-DMEK rate could be significantly reduced by the use of a peripheral mark (p = 0.002, p = 0.001, respectively). Re-DMEK due to primary graft failure was significantly associated with prior graft turning (p < 0.001). Both groups showed comparable values for visual acuity, central corneal thickness and endothelial cell count after a follow-up of 1 year. CONCLUSION Single peripheral triangular marking is a simple and cost-saving addition to EDM preparation to ensure the correct orientation of the graft intraoperatively and could lead to a significant reduction in graft turning and re-DMEK rate in this study.

中文翻译：

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DMEK中单条不对称鲨鱼鳍移植物定向后的临床结果。

目的 评估单个外围三角形标记的效果，以确保 DMEK 中正确的前后移植方向。方法 对因 Fuchs 内皮营养不良而计划接受 DMEK 的患者进行回顾性研究，并分为 2 个研究组：-M 组（n = 184）没有 EDM（内皮后弹力膜）标记，+M 组（n = 193）有三角形外围标记。随访时间为术后1年。结果 术后移植物翻转率和 Re-DMEK 率可通过使用外围标记显着降低（分别为 p = 0.002，p = 0.001）。由于原发性移植失败导致的 Re-DMEK 与先前的移植物转向显着相关（p < 0.001）。在 1 年的随访后，两组的视力、中央角膜厚度和内皮细胞计数显示出相当的数值。