PURPOSE We aimed to demonstrate the patient demographics, etiologies and apraclonidine test results in adult Horner's syndrome. METHODS This retrospective study was performed by the analysis of medical data of patients who were given 0.5% apraclonidine test. Patients' past medical history, demographic data, etiologies, accompanying neurological findings and pharmacological test results were assessed. RESULTS Forty patients (21 females and 19 males) with a mean age of 50.3 ± 11.6 years were evaluated. Apraclonidine 0.5% test was positive in 37 patients (92.5%). An etiology could be identified in 20 patients (central [9 patients, 45%], preganglionic [9 patients, 45%] and postganglionic [2 patients, 10%]). Neurological findings accompanying Horner's syndrome were present in 8 patients. CONCLUSION Despite detailed investigations, in a significant number of patients with Horner's syndrome an underlying cause may not be detected. Among the identifiable lesions, central and preganglionic involvements are still the first leading causes of Horner's syndrome. In addition, apraclonidine test may not be positive in all patients and a negative response does not exclude Horner's syndrome.

中文翻译：

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对成人霍纳综合征的患者人口统计、病因和安乐定试验结果的评估。

目的 我们旨在展示成人霍纳综合征患者的人口统计学、病因和安可乐定测试结果。方法这项回顾性研究是通过分析接受0.5%安乐定试验的患者的医学资料进行的。评估了患者的既往病史、人口统计数据、病因、伴随的神经学检查结果和药理学测试结果。结果 对平均年龄为 50.3 ± 11.6 岁的 40 名患者（21 名女性和 19 名男性）进行了评估。安普乐定 0.5% 试验在 37 名患者 (92.5%) 中呈阳性。可以在 20 名患者中确定病因（中枢性 [9 名患者，45%]、节前 [9 名患者，45%] 和节后 [2 名患者，10%]）。8 名患者出现伴随霍纳综合征的神经系统检查结果。结论 尽管进行了详细的调查，在大量霍纳综合征患者中，可能无法检测到潜在原因。在可识别的病变中，中央和节前受累仍然是霍纳综合征的首要原因。此外，安乐定试验可能并非对所有患者都呈阳性反应，阴性反应不排除霍纳综合征。