A 71-year-old female with type B3 thymoma developed severe aplastic anemia. Anti-thymocyte globulin was administered with glucocorticoids and cyclosporin A as the treatment for aplastic anemia. Computed tomography scan revealed that thymoma apparently shrank and remained without regrowth for at least 7 months. As previously reported, glucocorticoid has therapeutic effects on thymoma especially with abundant lymphocytes. Anti-thymocyte globulin also depletes peripheral lymphocytes, but its efficacy in the treatment of thymoma is unknown. Anti-thymocyte globulin and glucocorticoids may have cooperated with each other in reducing thymoma in our case. More cases should be accumulated to elucidate the effects of anti-thymocyte globulin on thymoma.

一名患有 B3 型胸腺瘤的 71 岁女性出现严重的再生障碍性贫血。抗胸腺细胞球蛋白与糖皮质激素和环孢菌素 A 一起用于治疗再生障碍性贫血。计算机断层扫描显示胸腺瘤明显缩小，至少 7 个月没有再生。如前所述，糖皮质激素对胸腺瘤有治疗作用，尤其是对淋巴细胞丰富的胸腺瘤。抗胸腺细胞球蛋白也会消耗外周淋巴细胞，但其治疗胸腺瘤的功效尚不清楚。在我们的病例中，抗胸腺细胞球蛋白和糖皮质激素可能在减少胸腺瘤方面相互合作。应积累更多病例，阐明抗胸腺细胞球蛋白对胸腺瘤的作用。