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Mesoscale modeling and biocompatibility of nano-hydroxyapatite reinforced ultra-high molecular weight polyethylene composite
Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science ( IF 2 ) Pub Date : 2021-10-30 , DOI: 10.1177/09544062211050456
Nishant Verma 1 , Anand Kumar Keshri 2 , Himanshu Pathak 1 , Sunny Zafar 1 , Amit Prasad 2
Affiliation  

This work aims to implement an efficient and accurate computational model to predict elastoplastic properties of UHMWPE/nano-HA bio-composite. Mean-field (MF) homogenization and finite element (FE) techniques are implemented to predict the elastoplastic behavior of composite. The predicted results obtained by MF and FE were compared and validated experimentally by fabricating the specimen using microwave-assisted compression molding. The axial and transverse moduli were increased by 49% at a 20% weight fraction of nano-HA. The hardening modulus was also found to be increased by 67%. Further, Degree of crystallinity (Xc) of fabricated composite specimens was determined using differential scanning calorimetry analysis. It was found that the Xc increased 34% with the addition of 20% weight fraction of nano-HA. In vitro, direct contact cytotoxicity and antibacterial test were performed to determine cell adhesion and bacterial behavior of the composite.



中文翻译:

纳米羟基磷灰石增强超高分子量聚乙烯复合材料的中尺度建模和生物相容性

这项工作旨在实施一种高效且准确的计算模型来预测 UHMWPE/纳米 HA 生物复合材料的弹塑性。实施平均场 (MF) 均质化和有限元 (FE) 技术来预测复合材料的弹塑性行为。通过使用微波辅助压缩成型制造样品,比较和验证了 MF 和 FE 获得的预测结果。在纳米 HA 的重量分数为 20% 时,轴向和横向模量增加了 49%。还发现硬化模量增加了 67%。此外,使用差示扫描量热法分析确定制造的复合样品的结晶度(X c )。发现Xc添加 20% 重量分数的纳米 HA 增加了 34%。在体外,进行了直接接触细胞毒性和抗菌试验,以确定复合材料的细胞粘附和细菌行为。

更新日期:2021-10-30
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