Oral mucositis (OM) is a common, highly symptomatic complication of cancer therapy that affects patients' function, quality of life, and ability to tolerate treatment. In certain patients with cancer, OM is associated with increased mortality. Research on the management of OM is ongoing. Oral mucosal toxicities are also reported in targeted and immune checkpoint inhibitor therapies. The objective of this article is to present current knowledge about the epidemiology, pathogenesis, assessment, risk prediction, and current and developing intervention strategies for OM and other ulcerative mucosal toxicities caused by both conventional and evolving forms of cancer therapy.

中文翻译：

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口腔黏膜炎范围的扩大和抗癌治疗的口腔溃疡黏膜毒性

口腔黏膜炎 (OM) 是癌症治疗中常见的、高度症状性的并发症，会影响患者的功能、生活质量和耐受治疗的能力。在某些癌症患者中，OM 与死亡率增加有关。对 OM 管理的研究正在进行中。在靶向和免疫检查点抑制剂治疗中也报告了口腔黏膜毒性。本文的目的是介绍有关流行病学、发病机制、评估、风险预测的最新知识，以及针对 OM 和其他由常规和不断发展的癌症治疗形式引起的溃疡性黏膜毒性的干预策略以及当前和正在开发的干预策略。