Background

Cardiac implantable electronic device (CIED) implantation rates as well as the clinical and procedural characteristics and outcomes in patients with known active coronavirus disease 2019 (COVID-19) are unknown.

Objective

The purpose of this study was to gather information regarding CIED procedures during active COVID-19, performed with personal protective equipment, based on an international survey.

Methods

Fifty-three centers from 13 countries across 4 continents provided information on 166 patients with known active COVID-19 who underwent a CIED procedure.

Results

The CIED procedure rate in 133,655 hospitalized COVID-19 patients ranged from 0 to 16.2 per 1000 patients (P <.001). Most devices were implanted due to high-degree/complete atrioventricular block (112 [67.5%]) or sick sinus syndrome (31 [18.7%]). Of the 166 patients in the study survey, the 30-day complication rate was 13.9% and the 180-day mortality rate was 9.6%. One patient had a fatal outcome as a direct result of the procedure. Differences in patient and procedural characteristics and outcomes were found between Europe and North America. An older population (76.6 vs 66 years; P <.001) with a nonsignificant higher complication rate (16.5% vs 7.7%; P = .2) was observed in Europe vs North America, whereas higher rates of critically ill patients (33.3% vs 3.3%; P <.001) and mortality (26.9% vs 5%; P = .002) were observed in North America vs Europe.

Conclusion

CIED procedure rates during known active COVID-19 disease varied greatly, from 0 to 16.2 per 1000 hospitalized COVID-19 patients worldwide. Patients with active COVID-19 infection who underwent CIED implantation had high complication and mortality rates. Operators should take these risks into consideration before proceeding with CIED implantation in active COVID-19 patients.

中文翻译：

---

在活跃的 COVID-19 患者中植入心脏电子设备：一项国际调查的结果

背景

已知活动性冠状病毒病 2019 (COVID-19) 患者的心脏植入式电子设备 (CIED) 植入率以及临床和手术特征及结果尚不清楚。

客观的

本研究的目的是根据一项国际调查，收集有关在 COVID-19 活动期间使用个人防护设备执行的 CIED 程序的信息。

方法

来自 4 大洲 13 个国家的 53 个中心提供了 166 名接受 CIED 手术的已知活动性 COVID-19 患者的信息。

结果

133,655 名住院 COVID-19 患者的 CIED 手术率为每 1000 名患者 0 至 16.2 例（P <.001）。大多数装置的植入是由于高度/完全性房室传导阻滞 (112 [67.5%]) 或病态窦房结综合征 (31 [18.7%])。在研究调查的 166 名患者中，30 天并发症发生率为 13.9%，180 天死亡率为 9.6%。一名患者因手术直接导致死亡。在欧洲和北美之间发现了患者和程序特征以及结果的差异。老年人群（76.6 对 66 岁；P <.001）并发症发生率更高（16.5% 对 7.7%；P= .2) 在欧洲比在北美观察到，而在北美观察到的重症患者比例更高（33.3% 对 3.3%；P <.001）和死亡率（26.9% 对 5%；P = .002）对欧洲。

结论

已知活动性 COVID-19 疾病期间的 CIED 手术率差异很大，全世界每 1000 名住院 COVID-19 患者中有 0 到 16.2 例。接受 CIED 植入的活动性 COVID-19 感染患者的并发症和死亡率很高。在对活跃的 COVID-19 患者进行 CIED 植入之前，操作者应考虑这些风险。