To the Editor We read with great interest the results from the study by de Boniface et al, which indicated a significantly higher comorbidity burden in patients using mastectomy irrespective of postoperative radiotherapy, compared with those treated with breast-conserving surgery with radiotherapy in patients with early-stage breast cancer. Moreover, after stepwise adjustment for all covariates, overall survival and breast cancer–specific survival were significantly worse after mastectomy without radiotherapy and mastectomy with radiotherapy than after breast-conserving surgery plus radiotherapy. Based on these results, the authors stated that mastectomy should not be regarded as equal to breast conservation.

中文翻译：

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在保乳手术中根除潜在的转移转移

致编辑我们非常感兴趣地阅读了 de Boniface 等人的研究结果，该结果表明，与接受保乳手术和放疗的早期患者相比，接受乳房切除术的患者无论术后放疗的合并症负担显着增加。 -阶段乳腺癌。此外，在对所有协变量进行逐步调整后，与保乳手术加放疗相比，不接受放疗的乳房切除术和接受放疗的乳房切除术后的总生存率和乳腺癌特异性生存率明显更差。基于这些结果，作者表示不应将乳房切除术视为等同于保留乳房。