Purpose of review 

The purpose of this review is to discuss the contemporary body of literature examining the relationship between cerebrospinal fluid (CSF) and ophthalmic disease. This review focuses on diseases that have a pathogenesis related to the translaminar pressure difference, defined as the pressure difference between the orbital subarachnoid space (OSAS) and the intraocular pressure. The diseases discussed include glaucoma, idiopathic intracranial hypertension, and spaceflight associated neuro-ocular syndrome.

Recent findings 

The relationship between cerebrospinal and ophthalmic disease has been investigated for over 100 years. Recent research provides insight into the mechanisms that dictate CSF circulation in the OSAS and how alterations in these mechanism lead to disease. This review discusses these recent findings and their relationship to major ophthalmic diseases.

Summary 

The recent findings provide insight into diseases that have pathogenic mechanisms that are not fully understood. This information will help physicians gain a clearer understanding of the relationship between CSF and ophthalmic disease and guide future research.

中文翻译：

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脑脊液与眼科疾病

审查目的 

本综述的目的是讨论当代研究脑脊液 (CSF) 与眼科疾病之间关系的文献。本综述重点关注与跨层压差（定义为眼眶蛛网膜下腔 (OSAS) 和眼内压之间的压力差）发病机制相关的疾病。讨论的疾病包括青光眼、特发性颅内高压和航天相关的神经眼综合征。

最近的发现 

脑脊髓疾病和眼科疾病之间的关系的研究已有 100 多年的历史。最近的研究深入了解了 OSAS 中脑脊液循环的机制以及这些机制的改变如何导致疾病。这篇综述讨论了这些最新发现及其与主要眼科疾病的关系。

概括 

最近的研究结果提供了对致病机制尚未完全了解的疾病的深入了解。这些信息将帮助医生更清楚地了解脑脊液与眼科疾病之间的关系，并指导未来的研究。