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Unusual case of severe diarrhoea
Gut ( IF 24.5 ) Pub Date : 2023-01-01 , DOI: 10.1136/gutjnl-2021-325937
Genki Inoue 1, 2 , Shuji Yamamoto 3 , Nobuo Koh 1 , Takeshi Kuwada 1 , Yuki Nakanishi 1 , Ken Takahashi 1 , Hiroshi Seno 1
Affiliation  

A 56-year-old man with COVID-19 pneumonia, requiring mechanical ventilation and extracorporeal membrane oxygenation, was transferred to our hospital. He was successfully treated with dexamethasone and remdesivir, followed by favipiravir, and he was extubated on day 30. Eighteen days after admission, he developed severe watery diarrhoea (passing more than 7000 mL/day). Subsequently, he went into shock due to hypovolaemia and hypoalbuminaemia (2.3 g/dL), and norepinephrine and albumin administration were commenced. Contrast-enhanced CT showed thickening of the small and large intestinal walls without findings suggesting intestinal ischaemia, such as decreased bowel wall enhancement and mesenteric thrombosis (figure 1A). Sigmoidoscopy on day 32 (figure 1B) showed prominent detachment of the colonic mucosa, and peroral enteroscopy …

中文翻译:

不寻常的严重腹泻病例

一名患有 COVID-19 肺炎的 56 岁男性,需要机械通气和体外膜氧合,被转移到我们医院。他成功地接受了地塞米松和瑞德西韦治疗,随后接受了法匹拉韦治疗,并在第 30 天拔管。入院后 18 天,他出现严重的水样腹泻(排出量超过 7000 毫升/天)。随后,他因低血容量和低白蛋白血症 (2.3 g/dL) 而休克,并开始给予去甲肾上腺素和白蛋白。对比增强 CT 显示小肠壁和大肠壁增厚,但没有提示肠缺血的发现,例如肠壁增强减少和肠系膜血栓形成(图 1A)。第 32 天的乙状结肠镜检查(图 1B)显示结肠粘膜明显脱离,经口小肠镜检查……
更新日期:2022-12-07
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