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Social Functioning in Adults Born Very Preterm: Individual Participant Meta-analysis
Pediatrics ( IF 8 ) Pub Date : 2021-11-01 , DOI: 10.1542/peds.2021-051986
Yanyan Ni 1, 2 , Marina Mendonça 1 , Nicole Baumann 1 , Robert Eves 1 , Eero Kajantie 3, 4, 5, 6 , Petteri Hovi 3, 6 , Marjaana Tikanmäki 3, 4 , Katri Räikkönen 7 , Kati Heinonen 7, 8 , Marit S Indredavik 5 , Kari-Anne I Evensen 5, 9, 10 , Samantha Johnson 11 , Neil Marlow 2 , Dieter Wolke 12
Affiliation  

CONTEXT

There is a lack of research on individual perceptions of social experiences and social relationships among very preterm (VP) adults compared with term-born peers.

OBJECTIVE

To investigate self-perceived social functioning in adults born VP (<32 weeks’ gestation) and/or with very low birth weight (VLBW) (<1500g) compared with term-born adults (≥37 weeks’ gestation) using an individual participant data (IPD) meta-analysis.

DATA SOURCES

Two international consortia: Research on European Children and Adults born Preterm and Adults Born Preterm International Collaboration.

STUDY SELECTION

Cohorts with outcomes assessed by using the Adult Self-Report Adaptive Functioning scales (friends, spouse/partner, family, job, and education) in both groups.

DATA EXTRACTION

IPD from 5 eligible cohorts were collected. Raw-sum scores for each scale were standardized as z scores by using mean and SD of controls for each cohort. Pooled effect size was measured by difference () in means between groups.

RESULTS

One-stage analyses (1285 participants) revealed significantly lower scores for relationships with friends in VP/VLBW adults compared with controls ( –0.37, 95% confidence interval [CI]: –0.61 to –0.13). Differences were similar after adjusting for sex, age, and socioeconomic status ( –0.39, 95% CI: –0.63 to –0.15) and after excluding participants with neurosensory impairment ( –0.34, 95% CI: –0.61 to –0.07). No significant differences were found in other domains.

LIMITATIONS

Generalizability of research findings to VP survivors born in recent decades.

CONCLUSIONS

VP/VLBW adults scored their relationship with friends lower but perceived their family and partner relationships, as well as work and educational experiences, as comparable to those of controls.



中文翻译:

早产成人的社会功能:个体参与者荟萃分析

语境

与足月出生的同龄人相比,缺乏对极早产 (VP) 成年人的社会经历和社会关系的个人看法的研究。

客观的

使用个体参与者调查出生 VP(<32 孕周)和/或极低出生体重(VLBW)(<1500g)的成人与足月出生的成人(≥37 孕周)相比的自我感知社会功能数据(IPD)荟萃分析。

数据源

两个国际联盟:研究欧洲早产儿和成人早产儿和成人早产儿国际合作。

学习选择

在两组中使用成人自我报告自适应功能量表(朋友、配偶/伴侣、家庭、工作和教育)评估结果的队列。

数据提取

收集了来自 5 个符合条件的队列的 IPD。通过使用每个队列的对照组的平均值和 SD,将每个量表的原始总和分数标准化为z分数。通过组间平均值的差异 () 来衡量合并效应大小。

结果

一阶段分析(1285 名参与者)显示,与对照组相比,VP/VLBW 成年人与朋友的关系得分显着低于对照组(–0.37,95% 置信区间 [CI]:–0.61 至 –0.13)。在调整性别、年龄和社会经济地位(–0.39,95% CI:–0.63 至 –0.15)和排除神经感觉障碍的参与者(–0.34,95% CI:–0.61 至 –0.07)后,差异相似。在其他领域没有发现显着差异。

限制

研究结果对近几十年出生的副总裁幸存者的普遍性。

结论

VP/VLBW 成年人对他们与朋友的关系评分较低,但认为他们的家庭和伴侣关系以及工作和教育经历与对照组相当。

更新日期:2021-11-01
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