Introduction: Pilomatrixoma is a relatively rare, benign tumor arising from the hair root matrix. It is found frequently on the head and neck, with most involving the eyebrow in the periocular region. In contrast, eyelid pilomatrixoma is less common, and often clinically misdiagnosed. Here, we present clinical and histological data from 19 pilomatrixomas arising in the eyelid. Methods: The study represents a retrospective study of eyelid pilomatrixoma diagnosed at our institution since 1981. All slides were reviewed, and demographic as well as clinical data obtained. Results: Patient ages ranged from 2 to 63 years (mean 24 years), including 12 (63%) females and 7(37%) males. Eight (42%) and 4 (21%) cases arose in the first and second decades of life, respectively. Upper eyelid involvement was found in 14 (74 %) of cases. Microscopically, the tumors were characterize by basaloid and shadow cells accompanied by calcification and foreign body giant cells. Conclusions: Eyelid pilomatrixoma is rarely suspected clinically, and can be mistaken for cyst, chalazion, sebaceous carcinoma and other tumors. Physicians should consider the possibility of pilomatrixoma in the eyelid area, especially in children or young female patients. Complete excision is curative, and diagnosis can generally be established by histopathological examination.


中文翻译：

---

19例眼睑毛母细胞瘤的临床病理特征

简介：毛母质瘤是一种相对少见的良性肿瘤，起源于毛根基质。它经常出现在头部和颈部，最常见于眼周区域的眉毛。相比之下，眼睑毛母细胞瘤较少见，临床上常被误诊。在这里，我们展示了来自眼睑的 19 个毛母细胞瘤的临床和组织学数据。方法：该研究代表了自 1981 年以来在我们机构诊断出的眼睑毛母细胞瘤的回顾性研究。审查了所有幻灯片，并获得了人口统计数据和临床数据。结果：患者年龄范围为 2 至 63 岁（平均 24 岁），其中女性 12 例（63%），男性 7 例（37%）。8 (42%) 和 4 (21%) 例分别发生在生命的第一个和第二个十年。14 例 (74 %) 病例发现上眼睑受累。显微镜下，肿瘤以基底细胞和阴影细胞为特征，伴有钙化和异物巨细胞。结论：眼睑毛母质瘤临床疑诊少见，易误诊为囊肿、霰粒肿、皮脂腺癌等肿瘤。医生应考虑眼睑区域有毛母细胞瘤的可能性，尤其是儿童或年轻女性患者。完全切除可治愈，一般可通过组织病理学检查确定诊断。尤其是儿童或年轻女性患者。完全切除可治愈，一般可通过组织病理学检查确定诊断。尤其是儿童或年轻女性患者。完全切除可治愈，一般可通过组织病理学检查确定诊断。