Information is lacking concerning in-hospital echocardiography analysis of COVID-19 infection in Brazil. We evaluated echocardiographic parameters to predict a composite endpoint of mortality, pulmonary thromboembolism or acute renal failure. A prospective full echocardiographic study of consecutive patients hospitalized with COVID-19, single tertiary centre in Brazil. We correlated echocardiographic findings to biomarkers, clinical information, thoracic tomography, and in-hospital composite endpoint of mortality, pulmonary thromboembolism or renal failure. One hundred eleven patients from March to October 2020, 67 ± 17 years, 65 (58.5%) men, death was observed in 21/111 (18.9%) patients, 48 (43%) required mechanical ventilation, myocardial infarction occurred in 10 (9%), pulmonary thromboembolism in 7 (6.3%) patients, haemodialysis was required for 9 (9.8%). Echocardiography was normal in 51 (46%) patients, 20 (18%) presented with decreased left ventricle ejection, 18 (16.2%) had abnormal left ventricle global longitudinal strain, 35 (31%) had diastolic dysfunction, 6 (5.4%) had an E/e’ratio > 14, 19 (17.1%) presented with right ventricle dilated/dysfunction, 31 (28%) had pericardial effusion. The echocardiographic parameters did not correlate with mortality, biomarkers, clinical events. Tricuspid velocity was related to the composite endpoint of mortality, pulmonary thromboembolism or acute renal failure (p: 00.3; value: 2.65 m/s; AUC ROC curve: 0.739; sensitivity: 73.3; specificity: 66.7; CI: 0.95, inferior: 0.613; superior: 0,866). Among hospitalized patients with COVID-19, echocardiography was normal in 51(46%) patients, and 20 (18%) patients presented with a decreased left ventricle ejection fraction. Tricuspid velocity was related to the composite endpoint of mortality, pulmonary thromboembolism or acute renal failure.

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院内 COVID-19 感染超声心动图分析：巴西三级单中心经验

缺乏关于巴西 COVID-19 感染的院内超声心动图分析的信息。我们评估了超声心动图参数以预测死亡率、肺血栓栓塞或急性肾功能衰竭的复合终点。对巴西单一三级中心因 COVID-19 住院的连续患者进行的前瞻性全超声心动图研究。我们将超声心动图结果与生物标志物、临床信息、胸部断层扫描和院内死亡率、肺血栓栓塞或肾功能衰竭的复合终点相关联。2020 年 3 月至 10 月 111 名患者，67 ± 17 岁，65 (58.5%) 名男性，21/111 (18.9%) 名患者死亡，48 (43%) 名需要机械通气，10 (10) 名发生心肌梗死 ( 9%)，7 名 (6.3%) 患者出现肺血栓栓塞，9 (9.8%) 需要血液透析。51 名 (46%) 患者超声心动图正常，20 名 (18%) 左心室射血减少，18 名 (16.2%) 左心室整体纵向应变异常，35 名 (31%) 舒张功能障碍，6 名 (5.4%) E/e' 比 > 14，19 (17.1%) 名出现右心室扩张/功能障碍，31 (28%) 名出现心包积液。超声心动图参数与死亡率、生物标志物、临床事件无关。三尖瓣流速与死亡率、肺血栓栓塞或急性肾功能衰竭的复合终点相关（p：00.3；值：2.65 m/s；AUC ROC 曲线：0.739；敏感性：73.3；特异性：66.7；CI：0.95，劣质：0.613 ；上级：0,866）。在住院的 COVID-19 患者中，51 名（46%）患者的超声心动图正常，20 (18%) 名患者出现左心室射血分数降低。三尖瓣流速与死亡率、肺血栓栓塞或急性肾功能衰竭的复合终点有关。