Ocular Immunology and Inflammation ( IF 3.3 ) Pub Date : 2021-10-22 , DOI: 10.1080/09273948.2021.1980814 Usanee Seepongphun 1 , Wantanee Sittivarakul 1 , Wantanee Dangboon 1 , Rassamee Chotipanvithayakul 2
ABSTRACT
Purpose
To describe the clinical characteristics and longitudinal pattern of visual acuity (VA) of pediatric patients with uveitis at a tertiary center in Thailand.
Methods
We retrospectively reviewed the records of children with uveitis ≤16 years who presented to the clinic between January 2010 and June 2020.
Results
The mean age at onset was 9.1(±4.3) years; the main characteristics were chronic (64.4%), unilateral (68.6%), and panuveitis (39%). The common etiologies were ocular toxoplasmosis (11.9%), herpetic uveitis (10.2%), and ocular toxocariasis (6.8%). Further, 40% of the eyes presented with VA of ≤20/200; mean VA at baseline improved from 0.93 to 0.72 logMAR at 3 months after presentation (P < .001), the baseline VA of ≤20/200 was significantly associated with poor VA outcome at 1 year.
Conclusion
Chronic, unilateral, and panuveitis represented the majority of our children with uveitis. Infectious etiology was common. Significant VA improvement can be achieved with optimum management.
中文翻译:
泰国三级中心儿科人群的葡萄膜炎模式
摘要
目的
描述泰国一家三级中心葡萄膜炎儿科患者的临床特征和视力 (VA) 的纵向模式。
方法
我们回顾了 2010 年 1 月至 2020 年 6 月期间就诊的 16 岁以下葡萄膜炎儿童的记录。
结果
平均发病年龄为9.1(±4.3)岁;主要特征为慢性(64.4%)、单侧(68.6%)和全葡萄膜炎(39%)。常见的病因是眼弓形体病(11.9%)、疱疹性葡萄膜炎(10.2%)和眼弓蛔虫病(6.8%)。此外,40% 的眼睛视力≤20/200;就诊后 3 个月,基线时的平均 VA 从 0.93 logMAR 改善至 0.72 ( P < .001),≤20/200 的基线 VA 与 1 年时的不良 VA 结果显着相关。
结论
慢性、单侧和全葡萄膜炎代表了我们患有葡萄膜炎的大多数儿童。传染性病因很常见。通过最佳管理可以实现显着的 VA 改善。