ABSTRACT

Purpose

To describe the clinical characteristics and longitudinal pattern of visual acuity (VA) of pediatric patients with uveitis at a tertiary center in Thailand.

Methods

We retrospectively reviewed the records of children with uveitis ≤16 years who presented to the clinic between January 2010 and June 2020.

Results

The mean age at onset was 9.1(±4.3) years; the main characteristics were chronic (64.4%), unilateral (68.6%), and panuveitis (39%). The common etiologies were ocular toxoplasmosis (11.9%), herpetic uveitis (10.2%), and ocular toxocariasis (6.8%). Further, 40% of the eyes presented with VA of ≤20/200; mean VA at baseline improved from 0.93 to 0.72 logMAR at 3 months after presentation (P < .001), the baseline VA of ≤20/200 was significantly associated with poor VA outcome at 1 year.

Conclusion

Chronic, unilateral, and panuveitis represented the majority of our children with uveitis. Infectious etiology was common. Significant VA improvement can be achieved with optimum management.

中文翻译：

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泰国三级中心儿科人群的葡萄膜炎模式

摘要

目的

描述泰国一家三级中心葡萄膜炎儿科患者的临床特征和视力 (VA) 的纵向模式。

方法

我们回顾了 2010 年 1 月至 2020 年 6 月期间就诊的 16 岁以下葡萄膜炎儿童的记录。

结果

平均发病年龄为9.1（±4.3）岁；主要特征为慢性（64.4%）、单侧（68.6%）和全葡萄膜炎（39%）。常见的病因是眼弓形体病（11.9%）、疱疹性葡萄膜炎（10.2%）和眼弓蛔虫病（6.8%）。此外，40% 的眼睛视力≤20/200；就诊后 3 个月，基线时的平均 VA 从 0.93 logMAR 改善至 0.72 ( P < .001)，≤20/200 的基线 VA 与 1 年时的不良 VA 结果显着相关。

结论

慢性、单侧和全葡萄膜炎代表了我们患有葡萄膜炎的大多数儿童。传染性病因很常见。通过最佳管理可以实现显着的 VA 改善。