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Challenges for Programmatic Implementation of Oral Cholera Vaccine in India
The Journal of Infectious Diseases ( IF 6.4 ) Pub Date : 2021-09-21 , DOI: 10.1093/infdis/jiab465
Debjit Chakraborty 1 , Suman Kanungo 1 , Ranjan Kumar Nandy 2 , Alok Kumar Deb 1 , Asish Kumar Mukhopadhyay 2 , Shanta Dutta 2
Affiliation  

Cholera remains a major contributor of diarrheal diseases and leads to substantial morbidity and mortality, particularly in low socioeconomic settings. Nonavailability of a national cholera control plan in India, compounded by underreporting of cholera cases and deficient accurate cholera hotspot estimates, has made cholera control a challenge. Obstacles in the programmatic introduction of oral cholera vaccine (OCV) lie within the infrastructure—stockpile, costing, distribution system, cold-chain mechanism, vaccine logistics, and lack of strengthened surveillance systems for adverse events following immunization. Sustained political commitment along with collaboration of people working in the media will also determine the policy outcome of OCV introduction in India.

中文翻译:

印度口服霍乱疫苗计划实施的挑战

霍乱仍然是腹泻病的主要诱因,并导致大量发病率和死亡率,特别是在社会经济条件低下的情况下。印度没有国家霍乱控制计划,加上霍乱病例报告不足和霍乱热点估计不准确,使霍乱控制成为一项挑战。口服霍乱疫苗 (OCV) 计划性引入的障碍在于基础设施——库存、成本计算、分销系统、冷链机制、疫苗物流,以及缺乏针对免疫接种后不良事件的强化监测系统。持续的政治承诺以及媒体工作人员的合作也将决定 OCV 在印度引入的政策结果。
更新日期:2021-09-21
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