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Activity-based profiling in RNA
Nature Chemical Biology ( IF 14.8 ) Pub Date : 2021-10-21 , DOI: 10.1038/s41589-021-00879-3
Supuni Thalalla Gamage 1 , Jordan L Meier 1
Affiliation  

RNA modifications are emerging regulators of development and disease. A metabolic labeling approach using 5-fluorocytidine (5-FCyd) allows the mechanism-based profiling of several RNA-modifying enzymes and potentially links their activity to novel RNA targets.

中文翻译:

RNA 中基于活性的分析

RNA 修饰是发育和疾病的新兴监管机构。使用 5-氟胞苷 (5-FCyd) 的代谢标记方法允许对几种 RNA 修饰酶进行基于机制的分析,并可能将它们的活性与新的 RNA 靶标联系起来。
更新日期:2021-10-22
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