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A roadmap to creating ferroptosis-based medicines
Nature Chemical Biology ( IF 14.8 ) Pub Date : 2021-10-21 , DOI: 10.1038/s41589-021-00853-z
Kamyar Hadian 1 , Brent R Stockwell 2, 3
Affiliation  

Ferroptosis is a regulated form of non-apoptotic cell death implicated in pathological settings. To be exploited clinically, ferroptosis requires reagents that unequivocally detect ferroptosis in human and animal tissues. Such tools may enable development of ferroptosis-based medicines for diverse diseases.

中文翻译:

创建基于铁死亡的药物的路线图

铁死亡是一种与病理环境有关的非凋亡性细胞死亡的调节形式。要在临床上加以利用,铁死亡需要能够明确检测人体和动物组织铁死亡的试剂。这些工具可能有助于开发针对多种疾病的基于铁死亡的药物。
更新日期:2021-10-22
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