Diabetes increases the risk of premature mortality and considerably impacts on work productivity. We sought to examine the impact of diabetes in India, in terms of excess premature mortality, years of life lost (YLL), productivity-adjusted life years (PALYs) lost, and its associated economic impact.

A life table model was constructed to examine the productivity of the Indian working-age population currently aged 20–59 years with diabetes, followed until death or retirement age (60 years). The same cohort was resimulated, hypothetically assuming that they did not have diabetes. The total difference between the two cohorts, in terms of excess deaths, YLL and PALYs lost reflected the impact of diabetes. Data regarding the prevalence of diabetes, mortality, labor force dropouts, and productivity loss attributable to diabetes were derived from published sources.

In 2017, an estimated 54.4 million (7.6%) people of working-age in India had diabetes. With simulated follow-up until death or retirement age, diabetes was predicted to cause 8.5 million excess deaths (62.7% of all deaths), 42.7 million YLL (7.4% of total estimated years of life lived), and 89.0 million PALYs lost (23.3% of total estimated PALYs), equating to an estimated Indian rupee 176.6 trillion (U.S. dollars 2.6 trillion; purchasing power parity 9.8 trillion) in lost gross domestic product.

Our study demonstrates the impact of diabetes on productivity loss and highlights the importance of health strategies aimed at the prevention of diabetes.

糖尿病会增加过早死亡的风险，并显着影响工作效率。我们试图检查糖尿病在印度的影响，包括过早死亡、生命损失年数 (YLL)、生产力调整生命年数 (PALYs) 损失及其相关的经济影响。

构建了一个生命表模型，以检查目前 20-59 岁患有糖尿病的印度劳动年龄人口的生产力，直至死亡或退休年龄（60 岁）。相同的队列被重新模拟，假设他们没有糖尿病。就超额死亡、YLL 和 PALYs 损失而言，两个队列之间的总差异反映了糖尿病的影响。有关糖尿病患病率、死亡率、劳动力辍学和糖尿病导致的生产力损失的数据来自已发表的资料。

2017 年，印度估计有 5440 万（7.6%）工作年龄的人患有糖尿病。通过对死亡或退休年龄的模拟随访，预计糖尿病会导致 850 万超额死亡（占所有死亡人数的 62.7%）、4270 万 YLL（占预计总寿命的 7.4%）和 8900 万 PALY 损失（23.3 % 估计的 PALYs），相当于估计印度卢比 176.6 万亿（2.6 万亿美元；购买力平价 9.8 万亿）的国内生产总值损失。

我们的研究证明了糖尿病对生产力损失的影响，并强调了旨在预防糖尿病的健康策略的重要性。