To the Editor The ICAN trial has provided level 1 evidence favoring intrathoracic anastomosis after a total or hybrid minimally invasive esophagectomy. We commend the authors on a robust study design for a purely surgical trial. The quality control of the surgical technique before participation and later during the trial is meticulous and may lay the standard for future surgical trials.

中文翻译：

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结果的普遍性和对 ICAN 试验泄漏率的担忧

致编辑 ICAN 试验提供了有利于在全或混合微创食管切除术后进行胸内吻合的 1 级证据。我们赞扬作者为纯粹的手术试验进行了稳健的研究设计。参与前和试验后期的手术技术质量控制是细致的，可能为未来的手术试验奠定标准。