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A transcriptional relationship with a natural product disrupts mitochondrial biogenesis
Cell Chemical Biology ( IF 8.6 ) Pub Date : 2021-10-21 , DOI: 10.1016/j.chembiol.2021.10.002 Aaron T Wright 1
中文翻译:
与天然产物的转录关系破坏线粒体生物发生
更新日期:2021-10-21
Cell Chemical Biology ( IF 8.6 ) Pub Date : 2021-10-21 , DOI: 10.1016/j.chembiol.2021.10.002 Aaron T Wright 1
Affiliation
A limonoid natural product disrupts mitochondrial biogenesis and overcomes resistance. In this issue of Cell Chemical Biology, Cho et al. describe an anti-melanoma strategy in which a transcriptional target gene enables the anti-proliferative activity of the limonoid, harrpernoid D.
中文翻译:
与天然产物的转录关系破坏线粒体生物发生
柠檬苦素类天然产物破坏线粒体生物发生并克服抗性。在本期《细胞化学生物学》中,Cho 等人。描述了一种抗黑色素瘤策略,其中转录靶基因使柠檬苦素、harrpernoid D 的抗增殖活性成为可能。