Co-loaded (–)-epigallocatechin-3-gallate (EGCG) and quercetin double emulsions and hydrogel beads were prepared, and their structure, functions, and digestion characteristics were investigated. The double emulsion particles were adsorbed by the cross-linked chains of the hydrogel beads. The encapsulation efficiencies of EGCG and quercetin within the hydrogel beads were higher than those within the double emulsion, while the antioxidant activities of the double emulsions were higher than those of the hydrogel beads. A lower amount of free fatty acids (FFAs) was released from the hydrogel beads than that released from the double emulsions. The bioavailability of EGCG was higher in the hydrogel beads than those in the double emulsions, while the quercetin bioavailability was not significantly different expect for the ratio of 3:7. The hydrogel beads remained intact in the stomach; however, numerous oil spills occurred in the small intestine. These data may improve double-emulsion-based delivery systems for controlled lipolysis and the release of co-encapsulated hydrophilic and lipophilic bioactive compounds.

制备了共负载的 (-)-表没食子儿茶素-3-没食子酸酯 (EGCG) 和槲皮素双乳剂和水凝胶珠，并研究了它们的结构、功能和消化特性。双乳液颗粒被水凝胶珠的交联链吸附。EGCG和槲皮素在水凝胶珠中的包封率高于双乳，而双乳的抗氧化活性高于水凝胶珠。从水凝胶珠粒中释放出的游离脂肪酸 (FFA) 量低于双乳剂中释放出的游离脂肪酸 (FFA) 量。EGCG 在水凝胶珠中的生物利用度高于双乳剂，而槲皮素的生物利用度在 3:7 的比例下没有显着差异。水凝胶珠在胃中保持完整；然而，小肠发生了多次漏油事件。这些数据可能会改进基于双乳液的递送系统，用于受控脂肪分解和共包封的亲水性和亲脂性生物活性化合物的释放。