Linear regression equations to predict β-lactam, macrolide, lincosamide and fluoroquinolone minimum inhibitory concentrations from molecular antimicrobial resistance determinants in Streptococcus pneumoniae,Antimicrobial Agents and Chemotherapy

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Linear regression equations to predict β-lactam, macrolide, lincosamide and fluoroquinolone minimum inhibitory concentrations from molecular antimicrobial resistance determinants in Streptococcus pneumoniae
Antimicrobial Agents and Chemotherapy ( IF 4.9 ) Pub Date : 2021-10-18 , DOI: 10.1128/aac.01370-21
Walter Demczuk ₁ , Irene Martin ₁ , Averil Griffith ₁ , Brigitte Lefebvre ₂ , Allison McGeer ₃ , Gregory J Tyrrell ₄ , George G Zhanel ₅ , Julianne V Kus _{6,

7} , Linda Hoang ₈ , Jessica Minion ₉ , Paul Van Caeseele ₁₀ , Rita Raafat Gad ₁₁ , David Haldane ₁₂ , George Zahariadis ₁₃ , Kristen Mead ₁₄ , Laura Steven ₁₅ , Lori Strudwick ₁₆ , Michael R Mulvey ₁

Affiliation

National Microbiology Laboratory, Public Health Agency of Canadagrid.415368.d, Winnipeg, Manitoba, Canada.
Laboratoire de Santé Publique du Québec, Sainte-Anne-de-Bellevue, Quebec, Canada.
Toronto Invasive Bacterial Diseases Network (TIBDN), Department of Microbiology, Mount Sinai Hospital, Toronto, Ontario, Canada.
The Provincial Laboratory for Public Health (Microbiology), Edmonton, Alberta, Canada.
Department of Medical Microbiology and Infectious Diseases, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada.
Public Health Ontariogrid.415400.4, Toronto, Ontario, Canada.
Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.
British Columbia Centre for Disease Control, Vancouver, British Columbia, Canada.
Roy Romanow Provincial Laboratory, Regina, Saskatchewan, Canada.
Cadham Provincial Laboratory, Winnipeg, Manitoba, Canada.
Office of the Chief Medical Officer of Health, New Brunswick Department of Health, Fredericton, New Brunswick, Canada.
Queen Elizabeth II Health Science Centre, Halifax, Nova Scotia, Canada.
Newfoundland and Labrador Public Health Laboratory, St. John's, Newfoundland, Canada.
Queen Elizabeth Hospitalgrid.278859.9, Charlottetown, Prince Edward Island, Canada.
Stanton Territorial Hospital Laboratory, Yellowknife, Northwest Territories, Canada.
Yukon Communicable Disease Control, Whitehorse, Yukon, Canada.

Antimicrobial resistance in Streptococcus pneumoniae represents a threat to public health and monitoring the dissemination of resistant strains is essential to guiding health policy. Multiple-variable linear regression modeling was used to determine the ...

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