In Vitro Activity of Ceftibuten/VNRX-5236 against Urinary Tract Infection Isolates of Antimicrobial-Resistant Enterobacterales,Antimicrobial Agents and Chemotherapy

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In Vitro Activity of Ceftibuten/VNRX-5236 against Urinary Tract Infection Isolates of Antimicrobial-Resistant Enterobacterales
Antimicrobial Agents and Chemotherapy ( IF 4.9 ) Pub Date : 2021-10-18 , DOI: 10.1128/aac.01304-21
James A Karlowsky _{1,

2} , Meredith A Hackel ₁ , Daniel F Sahm ₁

Affiliation

Ceftibuten/VNRX-7145 is a cephalosporin/boronate β-lactamase inhibitor combination under development as an oral treatment for complicated urinary tract infections caused by Enterobacterales producing serine β-lactamases (Ambler class A, C and D). In vivo, ...

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