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Is muscle and protein loss relevant in long-term fasting in healthy men? A prospective trial on physiological adaptations
Journal of Cachexia, Sarcopenia and Muscle ( IF 8.9 ) Pub Date : 2021-10-20 , DOI: 10.1002/jcsm.12766
Claire Laurens 1, 2 , Franziska Grundler 3, 4 , Anthony Damiot 1 , Isabelle Chery 1 , Anne-Laure Le Maho 5 , Alexandre Zahariev 1 , Yvon Le Maho 1, 6 , Audrey Bergouignan 1, 7 , Guillemette Gauquelin-Koch 2 , Chantal Simon 8, 9 , Stéphane Blanc 1 , Françoise Wilhelmi de Toledo 3
Affiliation  

Fasting is attracting an increasing interest as a potential strategy for managing diseases, including metabolic disorders and complementary cancer therapy. Despite concerns of clinicians regarding protein catabolism and muscle loss, evidence-based clinical data in response to long-term fasting in healthy humans are scarce. The objective of this study was to measure clinical constants, metabolic, and muscular response in healthy men during and after a 10 day fast combined with a physical activity programme.

中文翻译:

肌肉和蛋白质损失与健康男性的长期禁食有关吗?生理适应的前瞻性试验

禁食作为一种管理疾病的潜在策略,包括代谢紊乱和补充癌症治疗,引起了越来越多的兴趣。尽管临床医生担心蛋白质分解代谢和肌肉损失,但针对健康人长期禁食的循证临床数据却很少。本研究的目的是测量健康男性在禁食 10 天期间和之后结合体育锻炼计划的临床常数、代谢和肌肉反应。
更新日期:2021-10-20
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