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Neurocognitive decline in cardiac surgery—Distraction rather than destruction?
Journal of Cardiac Surgery ( IF 1.6 ) Pub Date : 2021-10-20 , DOI: 10.1111/jocs.16099
Tulio Caldonazo 1 , Hristo Kirov 1 , Torsten Doenst 1
Affiliation  

A neurocognitive decline is an undesirable event that can be observed in patients after cardiac surgery. It has been related to the use of cardiopulmonary bypass (CPB). Minor embolic or hyperinflammatory mechanisms are thought to be responsible. In this issue of the Journal of Cardiac Surgery, the neurocognitive decline was observed in 22 of 30 patients after cardiac surgery with CPB. Repeatable neuropsychological status tests were used and scores 4 days after surgery were 5%–15% lower than before. Mechanistic investigations with glycemic control and transcriptomic and cytokine analyses failed to provide an explanation but the frequency of this observation is worrisome.

中文翻译:

心脏手术中的神经认知下降——分心而不是破坏?

神经认知下降是心脏手术后患者中可观察到的不良事件。它与体外循环 (CPB) 的使用有关。轻微的栓塞或过度炎症机制被认为是造成这种情况的原因。在本期 《心脏外科杂志》中,30 名 CPB 心脏手术患者中有 22 名出现神经认知下降。使用可重复的神经心理状态测试,手术后 4 天的分数比之前低 5%–15%。血糖控制和转录组学和细胞因子分析的机制研究未能提供解释,但这种观察的频率令人担忧。
更新日期:2021-12-01
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