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Exploring the neural correlates of (altered) moral cognition in psychopaths
Behavioral Sciences & the Law ( IF 2.568 ) Pub Date : 2021-10-15 , DOI: 10.1002/bsl.2539
Laura M Lenzen 1 , Maximilian R Donges 2 , Simon B Eickhoff 3, 4 , Timm B Poeppl 1
Affiliation  

Research into the neurofunctional mechanisms of psychopathy has gathered momentum over the last years. Previous neuroimaging studies have identified general changes in brain activity of psychopaths. In an exploratory meta-analysis, we here investigated the neural correlates of impaired moral cognition in psychopaths. Our analyses replicated general effects in the dorsomedial prefrontal cortex, lateral prefrontal cortex, fronto-insular cortex, and amygdala, which have been reported recently. In addition, we found aberrant brain activity in the midbrain and inferior parietal cortex. Our preliminary findings suggest that alterations in both regions may represent more specific functional brain changes related to (altered) moral cognition in psychopaths. Furthermore, future studies including a more comprehensive corpus of neuroimaging studies on moral cognition in psychopaths should re-examine this notion.

中文翻译:

探索精神病患者(改变的)道德认知的神经相关性

在过去的几年里,对精神病的神经功能机制的研究势头强劲。以前的神经影像学研究已经确定了精神病患者大脑活动的一般变化。在一项探索性荟萃分析中,我们在这里调查了精神病患者道德认知受损的神经相关性。我们的分析复制了最近报道的背内侧前额叶皮层、外侧前额叶皮层、额-岛叶皮层和杏仁核的一般影响。此外,我们在中脑和下顶叶皮质中发现了异常的大脑活动。我们的初步研究结果表明,这两个区域的变化可能代表了与精神病患者的(改变的)道德认知相关的更具体的大脑功能变化。此外,
更新日期:2021-12-17
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