Neoadjuvant intra-arterial cytoreductive chemotherapy is used for the treatment of lacrimal gland adenoid cystic carcinomas (ACC) to improve outcomes in this condition with an otherwise dismal prognosis. We share our experience in the management of an advanced case of ACC using a novel, highly targeted intra-arterial cytoreductive chemotherapy delivery technique involving both the internal and external carotid circulation, with an attempt to correlate the effect histologically. Refinement of the chemotherapy delivery using the tumor's vascular anatomy and appropriate blood vessel selection may lead to future globe sparing procedures without compromising survival.

中文翻译：

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泪腺腺样囊性癌的靶向新辅助动脉内化疗：使用凋亡肿瘤标志物的组织学相关性。

新辅助动脉内细胞减灭化疗用于治疗泪腺腺样囊性癌 (ACC)，以改善这种情况的预后，否则预后不佳。我们分享了我们使用一种涉及颈内动脉和颈外循环的新型、高度靶向的动脉内细胞减灭化疗递送技术来治疗晚期 ACC 病例的经验，并试图在组织学上将效果关联起来。利用肿瘤的血管解剖结构和适当的血管选择来改进化疗输送可能会导致未来在不影响生存的情况下进行全球保留手术。