Dr Susan Hou began her illustrious nephrology career at a time when pregnancy in women with chronic kidney disease (CKD) was hazardous and actively discouraged. Her pioneering research in women’s health provided much of the early outcome data that shaped our current understanding of CKD and pregnancy. Although many uncertainties regarding optimal management of this vulnerable patient group remain, recent decades have witnessed important advances and renewed interest in improving care for pregnant women with CKD. Many nephrologists have been inspired by Dr Hou’s lifetime of work and are grateful for her generous collaborations. In this In Practice Review, we honor her legacy by providing an update of current literature and clinical management guidance in the context of a clinical case vignette that challenges us to consider the many complex aspects to the counseling and care of women with CKD who desire a pregnancy.

Susan Hou 医生在患有慢性肾病 (CKD) 的女性怀孕是危险的并且受到积极劝阻的时候开始了她杰出的肾脏病学生涯。她在女性健康方面的开创性研究提供了许多早期结果数据，这些数据塑造了我们目前对 CKD 和妊娠的理解。尽管关于这一弱势患者群体的最佳管理仍然存在许多不确定性，但近几十年来在改善 CKD 孕妇护理方面取得了重要进展并重新引起了人们的兴趣。许多肾病学家都受到侯博士一生工作的启发，并对她的慷慨合作表示感谢。在这个实践评论中，我们通过在临床病例小插曲的背景下提供最新文献和临床管理指南来纪念她的遗产，这些小插曲挑战我们考虑对希望怀孕的 CKD 女性进行咨询和护理的许多复杂方面。