The causes of death among cancer patients are multifactorial, and the mechanisms that drive pathological conditions that are associated with, but take place outside of, the tumor are still poorly characterized. In this issue of Developmental Cell, Kim et al. (2021) identify a paraneoplastic syndrome that affects blood-brain barrier permeability and host survival.

中文翻译：

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打破障碍：肿瘤使大脑渗漏

癌症患者的死亡原因是多方面的，驱动与肿瘤相关但发生在肿瘤之外的病理状况的机制仍不明确。在本期Developmental Cell 中，Kim 等人。(2021) 确定了一种影响血脑屏障通透性和宿主存活的副肿瘤综合征。