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Evaluation of low gradient severe aortic stenosis: should we change our outlook in the analysis of clinical data?
Open Heart Pub Date : 2021-10-01 , DOI: 10.1136/openhrt-2021-001746
Ivan Corazza 1 , Margherita Zecchi 2 , Romano Zannoli 2
Affiliation  

Nowadays, technological progress has equipped clinicians with new useful devices for the collection, analysis and presentation of data. As a consequence, many diseases and pathological conditions have been studied in a more detailed way, sometimes with remarkable results. In fact, they are not always validated by the old physiological models. In this respect, we present the case of low gradient severe aortic stenosis, a condition characterised by a small aortic valve area and a low-pressure gradient. According to the mathematical and physical assumptions these readings are contradictory whereas the Doppler-echocardiography shows clearly the existence of such a situation. In this work, we have described the physiological base of this phenomenon and discussed the limitations of the technology used. In this work, we are going to analyse some conditions commonly observed in daily clinical practice in order to prompt a critical outlook in both clinicians and technicians about the instrumentations used and the methods applied. There are no data in this work.

中文翻译:

低梯度重度主动脉瓣狭窄的评估:我们应该改变临床数据分析的观点吗?

如今,技术进步为临床医生提供了新的有用设备来收集、分析和呈现数据。因此,以更详细的方式研究了许多疾病和病理状况,有时取得了显着的成果。事实上,它们并不总是被旧的生理模型验证。在这方面,我们介绍了低梯度严重主动脉瓣狭窄的情况,这种情况的特点是主动脉瓣面积小,压力梯度低。根据数学和物理假设,这些读数是矛盾的,而多普勒超声心动图清楚地显示了这种情况的存在。在这项工作中,我们描述了这种现象的生理基础,并讨论了所使用技术的局限性。在这项工作中,我们将分析日常临床实践中常见的一些情况,以促使临床医生和技术人员对所使用的仪器和应用的方法进行批判性的展望。在这项工作中没有数据。
更新日期:2021-10-12
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